|Immunohistochemistry (Paraffin) (IHC (P))||Assay-Dependent|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 191 of Human PDCD6|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27639 targets PDCD6 in IF and WB applications and shows reactivity with Human samples.
The PA5-27639 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 191 of Human PDCD6.
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ALG-2; apoptosis-linked gene 2 protein; Apoptosis-linked gene 2 protein homolog; apoptosis-linked gene-2; PEF1B; probable calcium-binding protein ALG-2; Programmed cell death protein 6
Gene Aliases: ALG-2; ALG2; PDCD6; PEF1B
UniProt ID: (Human) O75340
Entrez Gene ID: (Human) 10016
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