|Immunohistochemistry (IHC)||Assay dependent|
|Western Blot (WB)||1:500|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (Human) against a common sequence near the 250-325 amino acids downstream from the N terminal region of PDE10A.|
|Purification||Antigen affinity chromatography|
|Storage buffer||proprietary buffer|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-31145 detects PDE10A from mouse, rat, human samples.
PA1-31145 has been successfully used in immunohistochemistry, immunoprecipitation, Western blot applications.
The PA1-31145 immunogen is: Synthetic peptide (Human) against a common sequence near the 250-325 amino acids downstream from the N terminal region of PDE10A.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate (Fujishige et al., 2000 [PubMed 10998054]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dJ416F21.1 (phosphodiesterase 10A); dual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase; FLJ11894; FLJ25677; HSPDE10A; PDE10A2 brain-specific isoform; phosphodiesterase 10A1 (PDE10A1); phosphodiesterase 10A7 (PDE10A7); testis-specific phosphodiesterase PDE10A2
Gene Aliases: ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A; PDE10A19; Pde10a3
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.