|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 308 and 561 of Human PDE4C|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31154 targets PDE4C in WB applications and shows reactivity with Human samples.
The PA5-31154 immunogen is recombinant fragment corresponding to a region within amino acids 308 and 561 of Human PDE4C.
Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4C is a class IV cAMP-specific PDE (summary by Milatovich et al., 1994 [PubMed 8009369]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5'-cyclic phosphodiesterase 4C; cAMP-specific (phosphodiesterase E1 dunce homolog; cAMP-specific 3'; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; Drosophila); PDE21; phosphodiesterase 4C; phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila); phosphodiesterase E1 dunce homolog
Gene Aliases: DPDE1; PDE4C
UniProt ID: (Human) Q08493
Entrez Gene ID: (Human) 5143
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