|Immunoprecipitation (IP)||Assay Dependent|
|Tested Species reactivity||Bovine, Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Porcine heart PDH|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.
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Protein Aliases: diaphorase; Dihydrolipoamide dehydrogenase; Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex; Dihydrolipoyl dehydrogenase, mitochondrial; E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex; E3-binding protein; E3BP; Glycine cleavage system L protein; glycine cleavage system protein L; kinase isoenzyme 1; lipoamide; lipoamide dehydrogenase; lipoamide reductase; lipoyl dehydrogenase; Lipoyl-containing pyruvate dehydrogenase complex component X; mitochondrial pyruvate dehydrogenase; PDHE1-A type I; proX; pyruvate dehydrogenase complex, component X; pyruvate dehydrogenase complex, E1-alpha polypeptide 1; pyruvate dehydrogenase complex, E3-binding protein subunit; pyruvate dehydrogenase complex, lipoyl-containing component X; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 component alpha subunit; Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase E1 subunit; pyruvate dehydrogenase kinase; Pyruvate dehydrogenase kinase isozyme 1; Pyruvate dehydrogenase protein X component; Pyruvate dehydrogenase protein X component, mitochondrial
Gene Aliases: BOS_15094; BOS_26312; BOS_4234; DLD; DLDBP; DLDD; DLDH; E3; E3BP; GCSL; LAD; OPDX; PDHA; PDHA1; PDHAD; PDHCE1A; PDHX; PDX1; PHE1A; PHE3; proX
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