|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 299 of PEX19|
|Storage buffer||PBS, pH 7|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA5-17266 targets PEX19 in IHC (P) and WB applications and shows reactivity with Human and Mouse samples.
The MA5-17266 immunogen is recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 299 of PEX19.
Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 33 kDa housekeeping protein; 33kD; D1S2223E; HK33; housekeeping gene; housekeeping gene, 33kD; Peroxin-19; Peroxisomal biogenesis factor 19; Peroxisomal farnesylated protein; peroxisome biogenesis factor 19; PMP1; PMPI; PXF; PXMP1
Gene Aliases: D1S2223E; HK33; OK/SW-cl.22; PBD12A; PEX19; PMP1; PMPI; PXF; PXMP1
Molecular Function: storage protein
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