|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 392 and 784 of Human PFK|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28673 targets PFK (platelet) in WB applications and shows reactivity with Human and mouse samples.
The PA5-28673 immunogen is recombinant fragment corresponding to a region within amino acids 392 and 784 of Human PFK.
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 188.8.131.52). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 6-phosphofructokinase; 6-phosphofructokinase type C; 6-phosphofructokinase, platelet type; ATP-dependent 6-phosphofructokinase, platelet type; ATP-PFK; ATP:D-fructose 6-phosphate 1-phosphotransferase; PFK-C; PFKF; Phosphofructo-1-kinase isozyme C; Phosphofructokinase; phosphofructokinase 1; Phosphofructokinase, platelet type; Phosphohexokinase; platelet type
Gene Aliases: 1200015H23Rik; 9330125N24Rik; ATP-PFK; PFK-C; PFK-P; Pfkc; PFKF; PFKP
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