|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 16 amino acid peptide from N-Terminus of human PTGES.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Rabbit, Pig (100%) Hamster, Bovine (94%).
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glutathione S-transferase 1-like 1; MGST-IV; MGST1-L1; MGST1-like 1; MGST1L1; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; microsomal prostaglandin E synthase-1; MPGES; MPGES-1; MPGES1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; PGES; PIG12; PP102; PP1294; Prostaglandin E synthase; PTGES; TP53I12; tumor protein p53 inducible protein 12
Gene Aliases: MGST-IV; MGST1-L1; MGST1L1; MPGES; mPGES-1; MPGES1; PGES; PIG12; PP102; PP1294; PTGES; TP53I12
UniProt ID: (Human) O14684
Entrez Gene ID: (Human) 9536
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