|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 603 and 880 of Human PI3 kinase p101|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28661 targets PI3 kinase p101 in IHC (P) applications and shows reactivity with Human samples.
The PA5-28661 immunogen is recombinant fragment corresponding to a region within amino acids 603 and 880 of Human PI3 kinase p101.
Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit (Brock et al., 2003 [PubMed 12507995]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-bisphosphate 3-kinase regulatory subunit; F730038I15Rik; FOAP-2; p101; P101-PI3K; Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit; phosphatidylinositol-4; phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit; Phosphoinositide 3-kinase regulatory subunit 5; phosphoinositide-3-kinase, regulatory subunit 5; PI3-kinase p101 subunit; PI3-kinase regulatory subunit 5; Protein FOAP-2; PtdIns-3-kinase p101; PtdIns-3-kinase regulatory subunit
Gene Aliases: F730038I15Rik; FOAP-2; p101; P101-PI3K; PIK3R5
UniProt ID: (Human) Q8WYR1
Entrez Gene ID: (Human) 23533
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.