|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 93-123 amino acids from the N-terminal region of human PI3KC2G|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PI3KC2G belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; Phosphoinositide 3-Kinase-C2-gamma; phosphoinositide-3-kinase, class 2, gamma polypeptide; PI3K-C2-gamma; PTDINS-3-kinase C2 gamma
Gene Aliases: PI3K-C2-gamma; PI3K-C2GAMMA; PIK3C2G
UniProt ID: (Human) O75747
Entrez Gene ID: (Human) 5288
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