|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 270 and 484 of Human PIGA|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27740 targets PIGA in WB applications and shows reactivity with mouse samples.
The PA5-27740 immunogen is recombinant fragment corresponding to a region within amino acids 270 and 484 of Human PIGA.
This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: class A GlcNAc-inositol phospholipid assembly protein; class A protein; GLCNAC-PI synthesis protein; GPI anchor biosynthesis; GPI3; N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein; phosphatidylinositol glycan, class A; phosphatidylinositol N-acetylglucosaminyltransferase subunit A; phosphatidylinositol-glycan biosynthesis; Phosphatidylinositol-glycan biosynthesis class A protein; phosphatidylinositolglycan class A; PIG-A
Gene Aliases: AI194334; Pig-a; Piga
UniProt ID: (Mouse) Q64323
Entrez Gene ID: (Mouse) 18700
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