|Western Blot (WB)||0.2-0.6 ug/ml|
|Tested Species reactivity||Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (KHSQSRRPSSWRQEKITR) corresponding to the internal amino acids of PIN1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with canine, human and mouse based on sequence homology.
Peptidyl-prolyl cis/trans isomerases , such as PIN1, catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. PIN1 is the only PPIase that specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. PIN1-catalyzed conformational regulation has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, germ cell development, neuronal differentiation, and survival .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DOD; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; peptidyl-prolyl cis/trans isomerase, NIMA-interacting; PIN1; prolyl isomerase; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1; UBL5
Entrez Gene ID: (Rat) 298696
Molecular Function: isomerase
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.