|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human PJA2|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA-mediated long-term memory processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase Praja-2; Neurodap1; praja 2, RING-H2 motif containing; praja ring finger 2; praja ring finger 2, E3 ubiquitin protein ligase; Praja2; RING finger protein 131; RING-type E3 ubiquitin transferase Praja-2; RNF131
Gene Aliases: KIAA0438; Neurodap1; PJA2; RNF131
UniProt ID: (Human) O43164
Entrez Gene ID: (Human) 9867
Molecular Function: ubiquitin-protein ligase
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.