|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 399 and 704 of Human PLA2G6|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27945 targets PLA2G6 in WB applications and shows reactivity with Human samples.
The PA5-27945 immunogen is recombinant fragment corresponding to a region within amino acids 399 and 704 of Human PLA2G6.
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only two of them have been determined to date.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 85 kDa calcium-independent phospholipase A2; 85/88 kDa calcium-independent phospholipase A2; CaI-PLA2; calcium-independent phospholipase A2; cytosolic; Group VI phospholipase A2; GVI; GVI PLA2; INAD1; Intracellular membrane-associated calcium-independent phospholipase A2 beta; iPLA2; iPLA2-beta; IPLA2-VIA; NBIA2A; NBIA2B; neurodegeneration with brain iron accumulation 2; PARK14; patatin-like phospholipase domain containing 9; Patatin-like phospholipase domain-containing protein 9; phospholipase A2, group VI (cytosolic, calcium-independent); PLA2; PNPLA9
Gene Aliases: CaI-PLA2; GVI; INAD1; iPLA2; IPLA2-VIA; iPLA2beta; NBIA2; NBIA2A; NBIA2B; PARK14; PLA2; PLA2G6; PLPLA9; PNPLA9
UniProt ID: (Human) O60733
Entrez Gene ID: (Human) 8398
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