|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 78 and 521 of Human PNK|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28853 targets PNK in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28853 immunogen is recombinant fragment corresponding to a region within amino acids 78 and 521 of Human PNK.
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5 and apos; phosphorylation and 3 and apos; dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bifunctional polynucleotide phosphatase/kinase; DNA 5'-kinase/3'-phosphatase; EIEE10; Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP); MCSZ; PNK; Polynucleotide kinase-3'-phosphatase
Gene Aliases: AOA4; EIEE10; MCSZ; PNK; PNKP
UniProt ID: (Human) Q96T60
Entrez Gene ID: (Human) 11284
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