|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 236 and 562 of Human POM121|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27623 targets POM121 in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-27623 immunogen is recombinant fragment corresponding to a region within amino acids 236 and 562 of Human POM121.
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is an integral membrane protein that localizes to the central spoke ring complex and participates in anchoring the nuclear pore complex to the nuclear envelope. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: nuclear envelope pore membrane protein POM 121; nuclear envelope pore membrane protein POM 121A; nuclear pore membrane protein 121 kDa; nucleoporin Nup121; P145; POM121 membrane glycoprotein; POM121A; pore membrane protein of 121 kDa
Gene Aliases: 2610027A18Rik; C80273; mKIAA0618; P145; POM121A
Molecular Function: Molecular function unclassified
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