|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 1-27 amino acids from the N-terminal region of human POU2AF1|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
POU2AF1 is transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: associating factor 1; B-cell-specific coactivator OBF-1; BOB-1; class 2; OBF-1; OBF1; OCA-B; OCAB; OCT-binding factor 1; POU domain; POU domain class 2-associating factor 1; POU domain, class 2, associating factor 1
Gene Aliases: BOB1; OBF-1; OBF1; OCAB; POU2AF1
UniProt ID: (Human) Q16633
Entrez Gene ID: (Human) 5450
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