|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||0.1 µg/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant human protein purified from E.coli (His-PP1G)|
|Storage buffer||HEPES with 0.15M NaCl, 0.01% BSA, 50% glycerol|
|Contains||0.03% sodium azide|
A suggested positive control for this product is MOLT-4 cells.
Protein phosphatase-1 (PP1) is one of the major Ser/Thr protein phosphatases and is ubiquitous in eukaryotic cells. PP1 is localized to its site of action by interacting with targeting or regulatory proteins, a majority of which contains a primary docking site referred to as the RVXF/W motif. The catalytic subunit of PP1 exists as three isoforms, PP1a, PP1b, and PP1r. The PP1 catalytic subunits are small proteins of 37kDa, which are highly conserved, with their main differences falling in the C-term. The PP1 catalytic subunit exists in the cell in complex with a large number of targeting/regulatory subunits, thereby generating different enzyme forms that allow it to perform a diverse number of cellular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PP-1G; PP1C gamma 1; PP1C gamma 2; PP1G; PP1gamma; protein phosphatase 1, catalytic subunit, gamma isoform; protein phosphatase 1, catalytic subunit, gamma isozyme; Protein phosphatase 1C catalytic subunit; protein serine-threonine phosphatase catalytic subunit PP-1b; serine/threonine phosphatase 1 gamma; Serine/threonine protein phosphatase PP1-gamma catalytic subunit; Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Gene Aliases: dis2m1; PP-1G; PP1; PP1C; PPP1CC; Ppp1cc1; PPP1G
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