|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 54 and 256 of Human PR3|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30959 targets PR3 in WB applications and shows reactivity with Human samples.
The PA5-30959 immunogen is recombinant fragment corresponding to a region within amino acids 54 and 256 of Human PR3.
Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACPA; AGP7; azurophil granule protein 7; C-ANCA; C-ANCA antigen; CANCA; Leukocyte proteinase 3; MBN; MBT; Myeloblastin; neutrophil; Neutrophil proteinase 4; NP-4; NP4; P29; PR-3; PR3; serine proteinase; serine proteinase, neutrophil; Wegener autoantigen; Wegener granulomatosis autoantigen
Gene Aliases: ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3; PRTN3
UniProt ID: (Human) P24158
Entrez Gene ID: (Human) 5657
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.