|Immunohistochemistry (Paraffin) (IHC (P))||1:1000-1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (233 EGVQKASPLPHSPP 246) of PRAT4A protein.|
|Storage buffer||whole serum with 50% glycerol|
|Contains||0.025% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PRAT4A is a novel protein belonging to the canopy family with a saposin B-type domain. It is an accessory molecule required for microbial recognition by Toll-like receptor (TLR), and mediates TLR dependent immune responses. Though the exact function of PRAT4A is still unknown, reports suggest that it is associated with the immature form of TLR4 and regulates the cell surface expression of this TLR. PRAT4A, a secreted protein, also has a role in TLR4 maturation and glycosylation. PRATA4 is usually present in endoplasmic reticulum and plays an active role in regulating the subcellular distribution and response of multiple TLRs and is required for both innate and adaptive immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAG repeat containing; CAG/CTG 5; CAG4A; CTG repeat protein 4a; ERDA5; expanded repeat domain; Expanded repeat-domain protein CAG/CTG 5; HSPC084; PRAT4A; Protein associated with TLR4; protein associated with Toll-like receptor 4A; Protein canopy homolog 3; TNRC5; trinucleotide repeat containing 5; Trinucleotide repeat-containing gene 5 protein
Gene Aliases: CAG4A; CNPY3; CTG4A; ERDA5; HSPC084; PRAT4A; TNRC5; UNQ1934/PRO4409
UniProt ID: (Human) Q9BT09
Entrez Gene ID: (Human) 10695
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.