|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified recombinant GST fusion protein encoding aa 245-573 of rat Riz1.|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody also recognizes the isoform beta (Riz2) of PRDM2 (185 kDa).
PRDM2 is a 250-kD nuclear protein containing 8 zinc finger motifs. It contains an RB-binding motif that is related to that of the adenovirus E1A oncoprotein; RIZ also shares an antigenic epitope with the C terminus of E1A. It is expressed in human retinoblastoma cells and at low levels in all other human cell lines examined. Using fluorescence in situ hybridization, the PRDM2 gene has been mapped to 1p36. PRDM2 may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, skin, and lymphoid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GATA-3 binding protein G3B; GATA-3-binding protein G3B; KMT8; Lysine N-methyltransferase 8; MTB-ZF; MTE-binding protein; PR domain containing 2, with ZNF domain; PR domain zinc finger protein 2; PR domain-containing protein 2; retinoblastoma interacting zinc finger protein; retinoblastoma protein-binding zinc finger protein; Retinoblastoma protein-interacting zinc finger protein; RIZ1, MTBzf, G3b; Zinc finger protein RIZ; zinc-finger DNA-binding protein
Gene Aliases: 4833427P12Rik; E330024L24Rik; Gm1033; Gm19732; HUMHOXY1; KMT8; MTB-ZF; PRDM2; RIZ; RIZ1; RIZ2; Znfpr1c1
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