|Western Blot (WB)||1/500|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Synthetic peptide to residues 610-673 of human PRKCQ.|
|Purification||Antigen affinity chromatography|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-20874 detects PRKCQ in human and mouse samples.
PA1-20874 has been successfully used in Western blot procedures.
PA1-20874 immunogen is a synthetic peptide to residues 610-673 of human PRKCQ.
PRKCQ is a calcium-independent, novel isoform that is important in transducing signals in T lymphocytes. Interaction of a T lymphocyte with an antigen-presenting cell results in clustering of the T cell antigen receptor (TCR) and the recruitment of a large signaling complex to the site of cell-cell contact. PRKCQ is essential for TCR-mediated activation. PKC theta plays a role in pathways that link the TCR signaling complex to the activation of NF-kappa B in mature T lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC126514; MGC141919; nPKC-theta; PKC theta; PRKCT; Protein kinase C theta type; protein kinase C, theta; RP11-563J2.1
Gene Aliases: A130035A12Rik; AW494342; nPKC-theta; PKC-0; PKC-theta; Pkcq; PKCtheta; PRKCQ; PRKCT
Molecular Function: annexin calcium-binding protein calmodulin intracellular calcium-sensing protein kinase non-receptor serine/threonine protein kinase protein kinase transfer/carrier protein transferase
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