|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1978 and 2072 of Human PRP8|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28721 targets PRP8 in WB applications and shows reactivity with Human samples.
The PA5-28721 immunogen is synthetic peptide corresponding to a region within amino acids 1978 and 2072 of Human PRP8.
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 220 kDa U5 snRNP-specific protein; apoptosis-regulated protein 1; apoptosis-regulated protein 2; HPRP8; ortholog of S. cerevisiae Prp8p; p220; Pre-mRNA-processing-splicing factor 8; precursor mRNA processing protein; PRP8; PRP8 homolog; PRP8 pre-mRNA processing factor 8 homolog; PRPC8; spl; Splicing factor Prp8; U5 snRNP-specific protein (220 kD); U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p
Gene Aliases: HPRP8; PRP8; PRPC8; PRPF8; RP13; SNRNP220
UniProt ID: (Human) Q6P2Q9
Entrez Gene ID: (Human) 10594
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.