|Western Blot (WB)||0.1-0.3 ug/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (NRFQIATVTE) corresponding to the internal amino acids of PSMB4|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine and rabbit based on sequence homology.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 26 kDa prosomal protein; HsBPROS26; HsN3; Low molecular mass protein 3; Macropain beta chain; Multicatalytic endopeptidase complex beta chain; PROS26; proteasome (prosome, macropain) subunit, beta type, 4; proteasome beta 4 subunit; Proteasome beta chain; Proteasome chain 3; Proteasome subunit beta type-4; proteasome subunit HsN3; proteasome subunit, beta type, 4; PSMB4; RN3; testis tissue sperm-binding protein Li 79P
Gene Aliases: HN3; HsN3; Lmp3; PROS-26; Pros-27; PROS26; PSMB4
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