|Western Blot (WB)||0.5-1.5 ug/ml|
|Tested Species reactivity||Mouse, Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (WTDEKQLKEQN) corresponding to the internal amino acids of PTF1A|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with canine, rat and zebrafish based on sequence homology.
This gene encodes a protein that is a component of the pancreas transcription factor 1 complex and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bHLH transcription factor p48; bHLHa29; Class A basic helix-loop-helix protein 29; class II bHLH protein PTF1A; exocrine pancreas-specific transcription factor p48; p48 DNA-binding subunit of transcription factor PTF1; pancreas specific transcription factor, 1a; Pancreas transcription factor 1 subunit alpha; pancreas transcription factor1 p48 subunit; Pancreas-specific transcription factor 1a; PTF1-p48; PTF1A
Gene Aliases: BHLHA29; PACA; PAGEN2; PTF1-p48; PTF1A; PTF1P48
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