|Immunocytochemistry (ICC)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||8 - 16 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 14 amino acid peptide from N-terminal extracellular domain of human PTGER4 / EP4.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human (100%) Chimpanzee, Gorilla, Marmoset (93%) Gibbon, Monkey (86%).
The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EP4; EP4 prostaglandin receptor; EP4 subtype; EP4R; PGE receptor; PGE receptor EP4 subtype; PGE receptor, EP4 subtype; PGE2 receptor EP4 subtype; Prostaglandin E receptor 4; prostaglandin E receptor 4 (subtype EP4); Prostaglandin E2 receptor EP4 subtype; Prostanoid EP4 receptor; PTGER4
Gene Aliases: EP4; EP4R; PTGER2; PTGER4
UniProt ID: (Human) P35408
Entrez Gene ID: (Human) 5734
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