|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 13 amino acid peptide from 1st cytoplasmic domain of human PTGES.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Rabbit (100%) Marmoset, Dog, Elephant, Panda, Pike (92%).
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glutathione S-transferase 1-like 1; MGST-IV; MGST1-L1; MGST1-like 1; MGST1L1; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; microsomal prostaglandin E synthase-1; MPGES; MPGES-1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; PGES; PIG12; PP102; PP1294; Prostaglandin E synthase; TP53I12; tumor protein p53 induci; tumor protein p53 inducible protein 12
Gene Aliases: MGST-IV; MGST1-L1; MGST1L1; MPGES; mPGES-1; MPGES1; PGES; PIG12; PP102; PP1294; PTGES; TP53I12
UniProt ID: (Human) O14684
Entrez Gene ID: (Human) 9536
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.