|Immunofluorescence (IF)||1/200 - 1/1000|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human PTH1R expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-15676 targets PTH1R in IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15676 immunogen is purified recombinant fragment of human PTH1R expressed in E. Coli.
MA5-15676 detects PTH1R which has a predicted molecular weight of approximately 66kDa.
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone and for parathyroid hormone-like hormone . The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia , chondrodysplasia Blomstrand type , as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC138426; MGC138452; Parathyroid hormone 1 receptor; parathyroid hormone receptor 1; Parathyroid hormone/parathyroid hormone-related peptide receptor; parathyroid hormone/parathyroid hormone-related protein receptor; PFE; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTH1R; PTHR; PTHR1; seven transmembrane helix receptor
Gene Aliases: PFE; PTH1R; PTHR; PTHR1
UniProt ID: (Human) Q03431
Entrez Gene ID: (Human) 5745
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