|Immunoprecipitation (IP)||2 ug|
|Western Blot (WB)||1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant human protein purified from E.coli|
|Purification||Ammonium sulfate precipitation|
|Storage buffer||HEPES with 0.15M NaCl, 0.01% BSA, 50% glycerol|
|Contains||0.03% sodium azide|
A suggested positive control for this product is Bosc23 cell lysate transfected with Myc/His/PTPRR.
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ch-1 PTPase; Ch-1PTPase; ECPPT; NC-PTPCOM1; protein tyrosine phosphatase Cr1PTPase; protein tyrosine phosphatase, receptor type, R; protein-tyrosine phosphatase NC-PTPCOM1; Protein-tyrosine phosphatase PCPTP1; PTPRQ; R-PTP-R; Receptor-type tyrosine-protein phosphatase R
Gene Aliases: EC-PTP; ECPTP; PCPTP1; PTP-SL; PTPBR7; PTPRQ; PTPRR
UniProt ID: (Human) Q15256
Entrez Gene ID: (Human) 5801
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