|Western Blot (WB)||1:50-1:100|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 169-196 amino acids from human PTPa|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
This antibody is predicted to react with mouse and rat based on sequence homology.
PTPa is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Leukocyte common antigen-related peptide (protein tyrosine phosphate); protein tyrosine phosphatase, receptor type, alpha polypeptide; Protein-tyrosine phosphatase alpha; PTPA; PTPase-alpha; PTPLCA-related phosphatase; PTPRA; PTPRL2; R-PTP-alpha; receptor-type tyrosine-protein phosphatase alpha; Receptor-type tyrosine-protein phosphatase alpha [Precursor]; tyrosine phosphatase alpha
Gene Aliases: HEPTP; HLPR; HPTPA; HPTPalpha; LRP; PTPA; PTPRL2; R-PTP-alpha; RP4-534B8.1; RPTPA
UniProt ID: (Human) P18433
Entrez Gene ID: (Human) 5786
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