|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 46 and 259 of Human PURA|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31194 targets PURA in WB applications and shows reactivity with Human and mouse samples.
The PA5-31194 immunogen is recombinant fragment corresponding to a region within amino acids 46 and 259 of Human PURA.
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Pur alpha; PUR-ALPHA; PUR1; PURALPHA; purine-rich element binding protein A; Purine-rich single-stranded DNA-binding protein alpha; Transcriptional activator protein Pur-alpha
Gene Aliases: CAGER-1; MRD31; PUR-ALPHA; PUR1; PURA; PURALPHA; ssCRE-BP
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.