|Immunohistochemistry (IHC)||1:300 - 1:2000|
|Western Blot (WB)||1:300 - 1:2000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from aa region 180-220 of human Pejvakin conjugated to an immunogenic carrier protein was used as the antigen|
|Storage buffer||whole serum|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Glycerol (1:1) may be added for additional stability.
Reconstitute in 100ul of distilled water.
Essential in the activity of auditory pathway neurons. Defects in PJVK are the cause of non-syndromic sensorineural deafness autosomal recessive type 59 (DFNB59). DFNB59 is a form of sensorineural hearing impairment with absent or severely abnormal auditory brainstem response but normal otoacoustic emissions (auditory neuropathy or auditory dys-synchrony). Auditory neuropathies result from a lesion in the area including the inner hair cells, connections between the inner hair cells and the cochlear branch of the auditory nerve, the auditory nerve itself and auditory pathways of the brainstem. 'Pejvak' means 'echo' in Persian.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: autosomal recessive 59; Autosomal recessive deafness type 59 protein; Autosomal recessive deafness type 59 protein homolog; DFNB59; DFNB59 deafness; Pejvakin; PJVK
Gene Aliases: DFNB59; Gm1001; PJVK
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.