|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 896 and 1187 of Human Pez|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28302 targets Pez in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28302 immunogen is recombinant fragment corresponding to a region within amino acids 896 and 1187 of Human Pez.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. The specific function of this PTP has not yet been determined.
Protein Aliases: cytoskeletal-associated protein tyrosine phosphatase; PEZ; Protein-tyrosine phosphatase pez; Tyrosine-protein phosphatase non-receptor type 14
Gene Aliases: PEZ; PTP36; PTPD2; PTPN14
UniProt ID: (Human) Q15678
Entrez Gene ID: (Human) 5784