|ELISA (ELISA)||Assay Dependent|
|Radioimmune Assays (RIA)||Assay Dependent|
|Tested Species reactivity||Chemical|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Phosphatidylinositol-4,5-biphosphate (PIP2) from bovine spinal cord.|
|Storage buffer||PBS with 10% BSA|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-26438 detects PIP2.
MA1-26438 has been successfully used in radioimmune assay procedures.
The MA1-26438 immunogen is Phosphatidylinositol-4,5-biphosphate (PIP2) from bovine spinal cord.
Phosphatidylinositol 4,5-bisphosphate or PIP2 is an important second messenger for a number of signaling processes. When certain extracellular signals are received, Phosphilipase C cleaves phosphatidylinositol into DAG and PIP2. PIP2 has been shown to interact with actin structural proteins including profiling, gelsolin, and cofilin, and demonstrates regulatory function of actin polymerization. It has also been shown to regulate vesicular transport by interacting with proteins like ADP-ribosylation factor and phospholipase D. PIP2 has also been shown to significantly affect intracellular calcium concentrations, which also regulate a variety of activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C45H85O19P3; Phosphatidylinositol Diphosphate; PIP2
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