|Western Blot (WB)||1:500-1:2000|
|Tested Species reactivity||Human, Rat, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from human CREB around the phosphorylation site of Serine 142|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: active transcription factor CREB; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element binding protein; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CREB-1; CREB1; cyclic AMP-responsive element-binding protein 1; transactivator protein; Y protein
Gene Aliases: 2310001E10Rik; 3526402H21Rik; AV083133; CREB; Creb-1
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