|Western Blot (WB)||1:500-1:2000|
|Tested Species reactivity||Human, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from human CDC25B around the phosphorylation site of Serine 353|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC25HU2; CDC25M2; dual specificity phosphatase Cdc25B; EC 126.96.36.199; M-phase inducer phosphatase 2; MPIP2
Gene Aliases: RP5-1009E24.3
UniProt ID: (Human) P30305
Entrez Gene ID: (Human) 994
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