|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide sequence around phosphorylation site of tyrosine 24 (G-A-Y(p)-G-K) derived from Human CDK6.|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
A suggested positive control for Western blot is 293 cells; suggested positive control for IHC is human colon carcinoma; suggested positive control for ICC/IF is Hela cells.
Cyclin-dependent kinase 6 (p40cdk6 also known as PLSTIRE) belongs to a family of proteins designated as cdks are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression.
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Protein Aliases: Cell division protein kinase 6; CR2 protein kinase; CRK2; Cyclin-dependent kinase 6; PLSTIRE; Serine/threonine-protein kinase PLSTIRE
Gene Aliases: 5830411I20; AI504062; CDK6; CDKN6; Crk2; MCPH12; PLSTIRE
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