|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y(p)-E-T) derived from Human coflin1/cofilin2.|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
A suggested positive control for Western blot is mouse heart cells; suggested positive control for IHC is human breast carcinoma.
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
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Protein Aliases: 18 kDa phosphoprotein; CFL; CFL-1; cofilin; Cofilin 1; cofilin 1 (non-muscle); cofilin 2 (muscle); Cofilin, muscle isoform; Cofilin, non-muscle isoform; Cofilin-1; Cofilin-2; Cofilin1; epididymis secretory protein Li 15; muscle isoform; NEM7; nemaline myopathy type 7; non-muscle isoform; p18
Gene Aliases: AA959946; CFL; CFL1; CFL2; Cof; cofilin; HEL-S-15; n-cofilin; NEM7
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