|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide sequence around phosphorylation site of tyrosine 779/833 (E-A-Y(p)-T-T)/(Q-D-V(p)-I-K) derived from Human EPHA3/4/5.|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
A suggested positive control for IHC is human brain tissue.
These proteins belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.
Protein Aliases: Brain-specific kinase; CEK-7; CEK7; eck-like sequence 1; EHK-1; EHK1; EK4; EK7; EK8; EPH homology kinase 1; EPH-like kinase 4; EPH-like kinase 7; EPH-like kinase 8; Eph-like tyrosine kinase 1; EPHA5; Ephrin type-A receptor 3; Ephrin type-A receptor 4; Ephrin type-A receptor 5; ETK1; HEK; HEK4; HEK7; HEK8; Human embryo kinase; human embryo kinase 1; receptor protein-tyrosine kinase HEK7; receptor protein-tyrosine kinase HEK8; rEK4; SEK; testicular tissue protein Li 64; TYRO1; TYRO1 protein tyrosine kinase; TYRO4; TYRO4 protein tyrosine kinase; tyrosine-protein kinase receptor EHK-1; Tyrosine-protein kinase receptor ETK1; Tyrosine-protein kinase receptor MPK-3; tyrosine-protein kinase receptor REK4; Tyrosine-protein kinase receptor SEK; Tyrosine-protein kinase receptor SEK-1; Tyrosine-protein kinase TYRO1; Tyrosine-protein kinase TYRO4
Gene Aliases: 2900005C20Rik; AI385584; AI854630; AW125296; AW492086; BSK; Cek4; CEK7; Cek8; EHK-1; EHK1; EK4; EK7; Ekh1; Els1; Els1.; End3; EPHA3; EPHA4; EPHA5; ETK; ETK1; HEK; HEK4; HEK7; HEK8; Mek4; rb; Rek4; Rek7; SEK; Sek1; TYRO1; TYRO4