|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic phosphopeptide derived from human FANCA around the phosphorylation site of Ser1149 (D-P-SP-L-M)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
FANCA (Fanconi anemia group A protein) is a DNA repair protein. It may function as a cell cycle checkpoint or in postreplication repair. FANCA may be important for the maintenance of chromosome stability and reparation of interstrand DNA cross linkages. Defects in this protein result in a disease state, Fanconi anemia, an autosomal recessive disorder. Fanconi anemia results in many congenital malformations and predisposition to malignant formations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: complementation group H; FA-H; FA1; FACA; FAH; FANCH; Fanconi anemia; Fanconi anemia group A protein; Fanconi anemia, complementation group A; Fanconi anemia, complementation group H; Fanconi anemia, type 1; Protein FACA; type 1
Gene Aliases: FA; FA-H; FA1; FAA; FACA; FAH; FANCA; FANCH
UniProt ID: (Human) O15360
Entrez Gene ID: (Human) 2175
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.