|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide sequence around phosphorylation site of tyrosine 642(I-D-Y(p)-Y-K) derived from Human FGFR4 .|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
A suggested positive control for Western blot is JK cells.
FGFR4 (Fibroblast Growth Factor Receptor 4), is a member of the FGFR family of receptor tyrosine kinases. This family regulates a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR4 protein interacts with specific growth factors to conduct signals from the environment outside the cell to the nucleus. FGFR4 gene plays a role in the development and maintenance of foveal cones in the light-sensitive layer of the retina.
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Protein Aliases: CD334; CTLA-2-beta protein; FGF Receptor 4; FGFR-4; Fibroblast Growth Factor Receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; protein-tyrosine kinase; Protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Gene Aliases: CD334; Fgfr-4; FGFR4; JTK2; Mpk-11; TKF
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