|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 30 and 39 of Human Histone H1.4|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31907 targets Phospho-Histone H1.4 pSer35 in IF and WB applications and shows reactivity with Human samples.
The PA5-31907 immunogen is synthetic peptide corresponding to a region within amino acids 30 and 39 of Human Histone H1.4.
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dJ221C16.5; H1 histone family; H1 histone family, member 4; H1.4; H1F4; histone 1; histone 1, H1e; Histone H1.4; Histone H1b; Histone H1s-4; member 4
Gene Aliases: dJ221C16.5; H1.4; H1E; H1F4; H1s-4; HIST1H1E
UniProt ID: (Human) P10412
Entrez Gene ID: (Human) 3008
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