|Western Blot (WB)||1:500-1:2000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthesized peptide derived from human HSL around the phosphorylation site of Serine 855/554|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.5, with 50% glycerol|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
This antibody detects isoform 1 (phospho-HSL pSer855, predicted molecular weight 116.6kDa) and isoform 2 (phospho-HSL pSer554, predicted molecular weight 84.1kDa).
In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hormone - sensitive lipase testicular isoform; Hormone-sensitive lipase; hormone-sensitive lipase testicular isoform; HSL; lipase E; LIPE
Gene Aliases: 4933403G17Rik; HSL; LHS
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