|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic phosphopeptide derived from human MAD1 around the phosphorylation site of Ser428 (E-Y-SP-P-Q)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homolog-like 1; HsMAD1; MAD1 mitotic arrest deficient-like 1; MAD1-like protein 1; Mitotic arrest deficient 1-like protein 1; Mitotic checkpoint MAD1 protein homolog; Mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1; mitotic-arrest deficient 1, yeast, homolog-like 1; PIG9; Tax-binding protein 181; TP53I9; tumor protein p53 inducible pr; tumor protein p53 inducible protein 9; TXBP181; yeast
Gene Aliases: MAD1; MAD1L1; PIG9; TP53I9; TXBP181
UniProt ID: (Human) Q9Y6D9
Entrez Gene ID: (Human) 8379
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