|Western Blot (WB)||1:1000|
|Tested Species reactivity||Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1244 of rat GRIN2C conjugated to KLH|
|Storage buffer||0.1M HEPES, pH 7.5, with 50% glycerol, 0.1mg/ml BSA, 0.15M NaCl|
This antibody is predicted to react with bovine and canine based on 100% sequence homology.
This antibody contains enough material to conduct 10 mini-Western blots.
The NMDA Receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of th NMDAR2 (NR2 A-D) subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GluN2C; GluRepsilon3; Glutamate [NMDA] receptor subunit epsilon-3; Glutamate NMDA receptor subunit epsilon-3; Glutamate receptor ionotropic NMDA 2C; Glutamate receptor ionotropic, NMDA 2C; glutamate receptor, ionotropic, NMDA2C; Grin2c; N-methyl D-aspartate receptor subtype 2C; N-Methyl-D-Aspartate Receptor Type 2C; NMDA glutamate receptor; NMDAR2C; NR2C
Gene Aliases: GluN2C; Grin2c; NMDAR2C; NR2C
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.