|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide sequence around phosphorylation site of Serine 104(I-P-S(p)-A-K) derived from Human PEA-15.|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
A suggested positive control for Western blot is COS7 cells; suggested positive control for IHC is human heart tissue.
Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 15 kDa phosphoprotein enriched in astrocytes; 15kD; Astrocytic phosphoprotein PEA-15; homolog of mouse MAT-1 oncogene; mammary transforming gene 1; mammary transforming gene 1, mouse, homolog of; OTTHUMP00000029887; PED; Phosphoprotein enriched in astrocytes; phosphoprotein enriched in astrocytes 15; phosphoprotein enriched in astrocytes 15A; Phosphoprotein enriched in diabetes
Gene Aliases: HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PEA15; Pea15a; PED; Pkcs15
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