|Dot blot (DB)||1:500|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y281 of human SLAMF1|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
SLAMF1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD150; CD150 antigen; CDw150; IPO-3; Signaling lymphocytic activation molecule; Signaling lymphocytic activation molecule [Precursor]; SLAM; SLAM family member 1; SLAMF1
Gene Aliases: CD150; CDw150; SLAM; SLAMF1
UniProt ID: (Human) Q13291
Entrez Gene ID: (Human) 6504
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