|Western Blot (WB)||1:1000|
|Tested Species reactivity||Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser187 of rat SNAP25 conjugated to KLH|
|Storage buffer||0.1M HEPES, pH 7.5, with 0.15M NaCl, 0.1mg/ml BSA, 50% glycerol|
This antibody is predicted to react with guinea pig, human, mouse, non-human primate and zebrafish based on 100% sequence homology.
This antibody contains enough material to conduct 10 mini-Western blots.
Synaptic vesicle membrane docking and fusion is mediated by SNAREs located on the vesicle membrane and the target membrane . The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: SNAP-25; SUP; Super protein; Synaptosomal-associated 25 kDa protein; Synaptosomal-Associated Protein 25; synaptosomal-associated protein, 25 kDa
Gene Aliases: Snap; SNAP-25a; SNAP-25B; Snap25
UniProt ID: (Rat) P60881
Entrez Gene ID: (Rat) 25012
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