|Western Blot (WB)||1:500-1:2000|
|Tested Species reactivity||Human, Rat, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from human Tyrosine Hydroxylase around the phosphorylation site of Serine 19|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dystonia 14; EC 184.108.40.206; TH isoform 3; TH isoform a; TH-4; TY3H; TYH; tyrosine 3-hydroxylase; Tyrosine 3-monooxygenase; tyrosine hydroxylase
Gene Aliases: DYT14; DYT5b; The; TYH
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