|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic phosphopeptide derived from human WASP around the phosphorylation site of Tyr290 (L-I-YP-D-F)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eczema-thrombocytopenia; IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); thrombocytopenia 1 (X-linked); U42471; Was; WASP; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrichsyndrome protein; Wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome protein homolog
Gene Aliases: IMD2; SCNX; THC; THC1; U42471; WAS; WASP; WASPA
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