|Western Blot (WB)||1:1000|
|Tested Species reactivity||Chicken, Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic phosphopeptide corresponding to residues surrounding pSer380 of human p90RSK|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Contains||<0.02% sodium azide|
It is not recommended to aliquot this antibody.
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 90 kDa ribosomal protein S6 kinase 2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1C; MAPKAPK-1c; mitogen-activated protein kinase-activated protein kinase 1C; OTTHUMP00000219225; OTTHUMP00000219227; OTTHUMP00000219228; p90-RSK 2; p90RSK2; pp90RSK3; Protein-tyrosine kinase Mpk-9; ribosomal protein S6 kinase alpha 2; Ribosomal protein S6 kinase alpha-2; ribosomal protein S6 kinase, 90kD, polypeptide 2; ribosomal protein S6 kinase, 90kDa, polypeptide 2; Ribosomal S6 kinase 3; RSK-3; S6K-alpha 2; S6K-alpha-2
Gene Aliases: 90kDa; D17Wsu134e; HU-2; MAPKAPK1C; p90-RSK3; p90rsk; p90RSK2; pp90rsk; pp90RSK3; Rps6ka-rs1; RPS6KA2; RSK; RSK3; S6K-alpha; S6K-alpha2
Molecular Function: annexin calcium-binding protein calmodulin intracellular calcium-sensing protein kinase non-receptor serine/threonine protein kinase protein kinase transfer/carrier protein transferase
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